منابع مشابه
Antifungal Agents
Continued advancement of medical science offers life-saving treatment options for a variety of hematologic, oncologic, and rheumatologic conditions. Immunosuppression, a common therapeutic side-effect, predisposes patients to invasive fungal infections, which are escalating in prevalence. The development of effective, welltolerated antifungals has lagged behind the advances of antibacterial the...
متن کاملAntifungal agents: Polyene, azole, antimetabolite, other and future agents
Antifungals have always been considered as one of the astonishing discoveries of the 20th century. This is correct, but the real marvel is the development of antifungal resistance in hospitals, communities, and the environment concomitant with their use. Fungal infections have emerged as an important clinical threat, with significant associated morbidity and mortality. This study is desig...
متن کاملLipid-based antifungal agents.
The spectrum of human mycoses ranges from superficial and local to disseminated and life-threatening infections. Opportunistic fungal infections of the immunocompromised host are difficult to treat and result in significant mortality. Antifungal drugs with a broad spectrum of activity along with acceptable efficacy and an optimal safety profile are an option for the treatment of these infection...
متن کاملPolyene Antifungal Agents
Dental Update – May 2000 165 Abstract: As both humans and fungi are eukaryotic organisms, antifungal agents affect their cellular metabolism. Thus, a relatively few antifungals with minimal toxicity and side-efects are available compared with a plethora of antibacterials. These agents currently prescribed in dentistry belong to two major groups, the polyenes (nystatin and amphotericin B) and th...
متن کاملSystemic Antifungal Agents
Systemic antifungal agents and their use for the therapy of invasive mycoses are discussed in this chapter. Many of these agents can also be used to treat the mucocutaneous forms of candidiasis, but those uses are discussed in detail in Chapter 257 and thus are mentioned only in passing here. Similarly, the therapy of the various forms of tinea and onychomycosis with topical agents or systemic ...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2010
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.99.1589